Video from an unspecified country in Asia depicts a child with Harlequin Ichthyosis – a genetic disease that turns skin of the affected person flaky and hard. The abnormalities in the skin also disrupt normal fluid retention within the body, and fail to act as a barrier that blocks bacteria and infection from readily entering the blood stream.
Note how inflexible the child is. Like it’s in a full body cast. I don’t know to what extent the brain is affected, but if the brain is fully functional and aware, the experience of being locked up within oneself must be awful.
Props to Best Gore member @african-angel for the video: